Amerxcan Journal of Physiology

نویسنده

  • J. A. BOULANT
چکیده

BOULANT, J. A., AND K. E. BIGNALL. Hypothalamic neuronal responses to peripheral and deep-body temperatures. Am. J. Physiol. 225(6) : 1371-1374. 1973.-Single-unit activity was recorded in the anterior hypothalamic-preoptic area of anesthetized rats and ground squirrels. The local thermosensitivity (i.e., impulses/set . “C) of 28 units was determined by their change in firing rate to changes in local temperature which was controlled by an implanted thermode. The responses of these units were also determined for peripheral warming and cooling which resulted in changes in skin and extrahypothalamic deep-body temperatures. Twelve single units showed activity changes during peripheral thermal stimulation; six of these were locally warm sensitive, three were cold sensitive, and three were temperature insensitive. Of the single units that were thermosensitive to local and extrahypothalamic temperatures, 78(% had the same type of thermal coefficient for both temperatures. The effect of peripheral thermal stimulation on local thermosensitivity was determined in nine units. In these units, an increase in firing rate due to peripheral stimulation was usually associated with a decrease in local thermosensitivity, suggesting a competition for neuronal excitation between local and peripheral facilitory inputs.

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تاریخ انتشار 2003